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Mosquito control centers handle large-scale infestations through coordinated and intensive interventions. They conduct comprehensive surveillance to map infestation hotspots and implement targeted treatments, such as aerial spraying for widespread areas and ground-based applications for localized control. Public education campaigns are intensified to encourage community participation in eliminating breeding sites and protecting against bites. Collaboration with local authorities and public health agencies ensures a unified response. Continuous monitoring and follow-up treatments help manage large-scale infestations effectively and prevent recurrence.